TOYOPEARL GigaCap S-650S, 35 µm, 250mL

TOYOPEARL GigaCap S-650 media are high capacity, high resolution cation exchange resins optimized for the capture and purification of both small and large proteins, including monoclonal antibodies. They are composed of polymethacrylate beads that have been chemically modified to provide a higher number of cationic binding sites and functionalized with sulfopropyl (S) strong cation exchange groups.

TOYOPEARL GigaCap S-650 resins can be used for high throughput capture, intermediate purification, and polishing process steps. They are available in two particle sizes: 75 µm (M-grade), and 35 µm (S-grade). TOYOPEARL GigaCap S-650 media also have excellent binding and elution kinetics, which results in a more concentrated protein fraction collected during the elution step.

TOYOPEARL GigaCap S-650M exhibits typical dynamic binding capacities greater than 150 g/L for human IgG and maintains its high capacity at increased linear velocities.

TOYOPEARL GigaCap S-650S has a dynamic binding capacity greater than 160 g/L for human IgG. This high capacity, combined with the 35 µm mean particle size, makes TOYOPEARL GigaCap S-650S ideal for high resolution applications.

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